tRNA

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 tRNA
Publisher: Gabby Terry
Editor: Grace Otting
Researchers: Brendan Hopkins and Rachel Yoo


RNA type: Transfer RNA(tRNA)

Components:
  • Phosphate group
  • Nitrogenous bases(Adenine, Uracil, Cytosine and Guanine)
  • Ribose(sugar)


Physical Description
  • Clover shape( do to the loops)
  • Upside down letter "L"
  • Sugar-Phosphate Backbone
  • Single-stranded

Job Description
  • tRNA is synthesized through the mRNA and its codons(translation)
  • made up of anticodons
  • anticodons are a guidelines for amino acids
  • synthesizes a sequence of amino acids to result in protein building

Photo
http://medical-dictionary.thefreedictionary.com/Trna+(transfer+RNA)
RNA_transfer-RNA.jpg



external image trna_diagram.gif

external image trna_diagram.gif
external image IrFhwVrnpB2_MSOpT8d2kitKGGSSDFppju9x1rjoDIsfyLc4MIThR5aQvZWh2_B4G4O4MVV5wTcbgdyti-ja4_FR7dLvQ3Ol0tuRnW9suJj56J8qODs


http://www.wiley.com/college/boyer/0470003790/structure/tRNA/trna_intro.htm



Where Is the Molecule Formed
  • tRNA is formed in the nucleus, before transferring into the cytoplasm to the ribosomes, for translation

Where is the Molecule found in the cell
  • ribosomes
  • cytoplasm

How does the molecule work?

  • tRNA is in charge of the major process of translation of protein synthesis. The mRNA and tRNA are translated in the nucleus, and then moves into the cytoplasm. Translation begins when the tRNA and mRNA come together in order to form the sequence of anticodons from the codons of mRNA. The translation now leads to elongation with the codon being paired with an amino acid. It begins with the codon AUG and MET (methionine), which are formed from complementary bases into amino acids. Elongation continues until the amino acid “STOP” directs the process to end. Now the Amino sequence is formed with the help of tRNA and its elongation of amino acids, or the production of a protein. Once the STOP codon is reached, the peptide chain is released from the ribosome.

Video:




Works Cited
"Concepts in Biochemistry - Structure Tutorials." Wiley. Web. 11 Apr. 2011. <http://www.wiley.com/college/boyer/0470003790/structure/tRNA/trna_intro.htm>.
"TRNA & Ribosomes." Rensselaer Polytechnic Institute (RPI). Web. 11 Apr. 2011. <http://rpi.edu/dept/bcbp/molbiochem/MBWeb/mb2/part1/trna.htm>.
"Where Is RNA Found?" Web. 11 Apr. 2011. <http://www.brighthub.com/science/genetics/articles/30613.aspx>.
"YouTube - TRNA with the Bio Boys." YouTube. Web. 11 Apr. 2011. <http://www.youtube.com/watch?v=gE46bMA0Z14>.